Founded by Dr. Obagi in 2007, ZO Skin Health, Inc.® was created to provide physicians and patients with the world’s most innovative and effective skin health solutions. As Medical director of ZO Skin Health INC.®, Dr. Obagi has created products with technologically advanced ingredients and even more effective formulations, designated into two categories: ZO® Skin Health and ZO® Medical. ZO® Skin Health products maintain the results of therapeutic treatments and provide effective daily skincare and protection from the environment, while ZO® Medical products have been optimized to treat a range of skin disorders and chronic conditions.

ZO Phase 1: Daily Skincare Program Generally for Ages 17-25

Phase1 Daily Skin Program

The first line of defense against fine lines and wrinkles is to keep skin hydrated and protected from damaging sun exposure. It starts with a basic skincare program that uses potent levels of high-performance ingredients to aid in the fight against the natural aging process. The Daily Skincare program is everyday skincare essential to help strengthen and maintain healthy looking skin. It is specifically formulated to:

  • Help preserve and maintain a more youthful- looking complexion
  • Help prevent future damage by protecting skin from the sun
  • Improve and maintain the appearance of even skin tone and finer pores
  • Keep skin hydrated

ZO Phase 2: Anti-Aging Program Generally for Ages 26-44

Phase 2 Anti Aging Program

This moderately aggressive program made with highly advanced anti-aging ingredients and technologies is designed to help reduce the appearance of early or significant signs of environmental and chronological aging. The Anti-Aging Program uses potent ingredients, concentrated formulas and aggressive delivery systems to improve and strengthen skin’s appearance and protect against future damage. It is specifically formulated to:

  • Help reduce the appearance of fine lines and wrinkles
  • Promote a more even-looking skin tone and finer pore appearance
  • Preserve and maintain a more youthful-looking complexion
  • Help prevent future skin damage by protecting against harmful effects of the sun

ZO Phase 3: Aggressive Anti-Aging Program Generally for Ages 45+

Phase 3 Aggressive ProgramDeeper lines and wrinkles, hyperpigmentation (age spots, and sun damage) and thinning skin with reduced elasticity and firmness all require more aggressive treatment. The Aggressive Anti-Aging Program features potent formulas with enzymes, a functional hydrator and antioxidants. It also contains a high concentration of retinol, a topical ingredient proven to mitigate the effect of both environmental and chronological skin aging. It is specifically formulated to:


  • Help reduce the appearance of deeper lines and wrinkles
  • Minimize the appearance of hyperpigmentation and age spots
  • Promote a more even-looking skin tone
  • Aid in strengthening the skin by keeping hydration at the proper level
  • Help maintain results achieved with lasers or medical treatments

    ZO Acne Prevention and Treatment Program

    Acne Prevention Treatment1When skin does not exfoliate as it should, dead cells build uo on the skin’s surface and inside the pores. The dead skin cells then mix with trapped oil and the pores become clogged, resulting in blackheads and whiteheads. The Acne Prevention + Treatment Program features essential ingredients to slow sebum activity and break down surface oils, while exfoliating dead skin cells to help repair surface damage, tighten pores and improve skin texture. It is specifically formulated to:

  • Control excess oil production
  • Remove dead skin cells
  • Stimulate healthy cell renewal
  • Boost skin’s natural production of collagen
  • Calm and soothe inflamed and irritated skin
  • ZO Multi-Therapy Hydroquinone System

    Designed by Zein Obagi, MD to treat several skin conditions:

    ZO MD Multi Therapy HQ2

  • Hyperpigmentation: Treats moderate to severe hyperpigmentation, especially melasma. Recommended as a starting point for treating melasma.
  • Severe texture damage: Treats severely dry, dull, rough and leathery textured skin to help soften skin and restore a smooth, healthy glow.
  • Sun damage: Treats severely dry, dull, leathery textures with visible sun spots and damage.
  • Pre/post-procedure skin conditioning: Provides improved outcomes and longer-lasting results when used 4-6 weeks before in-office procedures and 12 weeks afterwards.
  • General skin health restoration: Improves the overall quality, health and appearance of the skin.
  • ZO Skin Brightening Program for Hyperpigmentation Non-Hydroquinone

    ZO Skin Brightening ProgramThis skin brightening program is specifically designed to brighten skin tone and lessen the appearance of discoloration. Stabilized vitamin C promotes a more even skin tone and minimizes the appearance of lines and wrinkles. Mild enough for everyday use.

  • Ideal for improving the appearance of hyperpigmentation either when hydroquinone treatment is completed or contraindicated, or as maintenance
  • Ideal for non-specific discoloration (freckles, liver spots or uneven tone)
  • For use when skin brightening is desired
  • This program also reduces the appearance of fine lines and wrinkles.
  • Olluminate Intense Eye Repair

    Targeted eye treatment formulated to help repair and prevent signs of aging. Perfect for all skin types.Olluminate Intense Eye Repair1

  • Helps diminish the appearance of fine lines and wrinkles
  • Optical light diffusers reflect light to minimize imperfections
  • Protects against free radical damage
  • Helps reduce puffiness and discoloration
  • minimize the multiple signs of aging, including puffiness, dark circles and fine lines.
  • Revitatrol Epidermal Repair Cre’me

    Upload: December 21, 2016Delivers essential hydration and calming for post-procedure, compromised and severely dry or irritated skin. Rich hydrators replenish lipids and restore skin’s barrier while reducing the appearance of redness.

  • Dual-peptide formula supports natural skin renewal and improves the appearance of fine lines and wrinkles
  • Enhances skin re-epithelialization to accelerate recovery
  • Ideal for daily use under sunscreen
  • Retamax Active Vitamin A Micro Emulsion

    Upload: December 21, 2016This innovative retinol formula is blended with plant stem cell antioxidants and biometric proteins. It utilizes a micro-emulsion technology that helps reverse the signs of aging and aids in the prevention of future skin damage. It also improves skin texture and tone.

  • Helps reduce lines and wrinkles in the skin
  • Supports a more even skin tone
  • Provides antioxidant and anti-irritant properties
  • Helps skin renew itself
  • Aknetrol Acne Treatment

    Benzoyl Peroxide 10%

    Aknetrol0This maximum-strength, acne-fighting formula contains benzoyl peroxide (10%), tea tree oil, glycerin and antioxidants to help skin normalize sebum output. It immediately minimizes surface oil, reduces redness and helps prevent future breakouts. It also increases cellular turnover to help decrease the spread of bacteria and clears clogged pores.

  • Helps neutralize bacteria-causing acne/breakouts
  • Removes impurities
  • Clears clogged pores
  • Reduces redness
  • Aknebright Acne Spot and Pigmentation Treatment

    Upload: December 21, 2016This targeted acne and brightening treatment offers rapid relief from acne lesions and post-inflammatory hyperpigmentation. It features LiquiPatch technology and rollerball application for clean, easy and superior application penetration.

  • Helps reduce redness and irritation of papules and pustules
  • Dual purpose product – acne treatment and skin brightener
  • LiquiPatchTM technology helps deliver acne-fighting ingredients faster
  • Offects Correct + Conceal Acne Spot Treatment

    Available in Light & Medium

    Offects Correct Conceal LightThis corrector and concealer provides long-lasting matte coverage with a targeted spot treatment that attacks acne to clear up active breakouts. Our triple-action nourishing complex keep skin hydrated while helping to prevent post-acne marks. Advanced phyto-technology also helps calm and soothe red, irritated acne lesions.

  • Soft focus concealer provides an instant, natural, long-lasting matte coverage
  • Maximum strength acne medication treats & prevents acne on the surface of the skin and within the pore
  • Added tea tree oil helps keep skin clean
  • Offect TE-Pads Acne Pore Treatment

    Offects TE Pads1This daily leave-on treatment targets excess oils and clogged pores while controlling shine. They can be taken anywhere to help calm irritated skin and decrease breakouts at a moment’s notice.

  • Dual action exfoliation removes dead skin cells to prevent clogged pores
  • Reduces oiliness to help control acne and provide a clearer complexion
  • Calms and soothes irritated skin
  • Normacleanse Cleanser for Normal to Dry Skin

    Norma Cleanse 0A unique formulation that gently cleans and conditions the skin while setting the stage for effective treatment.

  • Helps remove surface dirt and oils
  • Soothes and nourishes the skin
  • Prepares the skin to receive therapeutic treatment
  • Oilacleanse Cleanser for Normal to Oily Skin

    Oilacleanse0This dual-action cleanser/exfoliator targets excess oil and impurities to purify skin and help prevent and clear acne. It refines the complexion, reduces the factors that contribute to skin irritation and helps decrease the level of bacteria on the skin’s surface.

  • Purifies and cleanses skin
  • Helps prevent pores from clogging
  • Aids in removing excess oils and impurities
  • Foamacleanse Gentle Foaming Cleanser for All Skin Types

    This fresh-foaming formula contains glycerin, meadowsweet and green tea. It deep cleans pores and dissolves excess oil with hydrating, anti-inflammatory and anti-oxidant benefits.

  • Helps remove makeup
  • Deep cleans skin to remove oil and impurities
  • Leaves the skin feeling refreshed
  • Offects Exfoliating Polish

    This skin-smoothing scrub contains ultra-fine magnesium crystals to exfoliate dead skin cells and increase epidermal turnover for a clear, smooth and even-toned complexion. Vitamins A, C, E, and C esters provide antioxidant benefits to help maintain the skin’s barrier function.

  • Physical exfoliation with magnesium crystals provides at-home benefits of microdermabrasion
  • Instantly polishes skin to restore smoother texture and healthy glow
  • Removes dead skin cells to prevent clogged pores
  • Enhances penetration of active ingredients
  • Offects Sulfur Masque Ace Treatment

    This natural clay-based formula delivers maximum strength sulfur medication to treat and prevent acne eruptions on the face, neck, chest and back. Kaolin and bentonite purify pores and help absorb excess sebum that can lead to future breakouts. Skin hydrators help combat dryness that can occur when using aggressive acne treatments.

  • Absorbs surface oils and helps reduce oiliness
  • Helps prevent clogged pores
  • Can be used as a spot treatment on blemishes
  • Balatone Calming Toner pH Balancer

    This calming toner is designed to invigorate dry, weak skin. It also removes impurities and balances the skin’s pH to optimize the penetration of therapeutic treatments.

  • Helps soothe and repair sensitive/weak skin
  • Gentle, cooling action adds comfort
  • Ossential Daily Power Defense

    A MUST FOR EVERYONE! Time-released retinol, antioxidants and specialized DNA-repairing enzymes work around the clock to help minimize UV oxidative damage and uneven pigmentation. They also help restore skin function and elasticity while stimulating collagen production to help diminish fine lines and wrinkles.

  • Provides antioxidant protection to combat free radical damage
  • Helps tighten and firm the skin
  • Promotes skin health
  • Helps support skin’s natural mechanism to repair damage and protect against future skin
  • Ossential Growth Factor Serum Plus

    This lightweight formula features two growth factors that support collagen and elastin production for increased skin density. Additionally, a combination of retinol and amino acids stimulates cellular function, reduces collagen degradation and restores elasticity.

  • Helps reduce the appearance of expression lines, lines and wrinkles
  • Strengthens weak skin and minimizes irritation
  • Restores hydration and enforces the skin’s protective barrier
  • Helps promote healthier, brighter skin
  • Ossential Advanced Radical Night Repair

    1% Retinol

    Using a high concentration of retinol in a patented, slow-release microdelivery system, this formula is designed to deliver rapid results to address multiple signs of skin aging. It also helps healthy, new skin cells to emerge to the surface for a smoother texture and radiant appearance.

  • An anhydrous (water-free) formulation ensures stability for maximum anti-aging benefits
  • Helps improve skin’s brightness, reduces brown spots and provides a more even tone
  • Provides antioxidant protection to neutralize free radical damage
  • Combats irritation to help calm and soothe the skin
  • Ossential C-Bright Serum 10% Vitamin C

    This illuminating formula provides a potent dose of pure, stabilized ascorbic acid (10%) to rapidly retexturize skin surface pigmentation for a brighter, more even-toned complexion. It also helps prevent new pigmentation formation by up to 80%, reduces wrinkle depth and provides superior antioxidant protection.

  • Helps remove surface discoloration
  • Helps prevent new pigment from forming
  • Powerful antioxidants help defend against environmental triggers that cause pigmentation
  • Helps minimize the appearance of fine lines and wrinkles
  • Oclipse Sunscreen + Primer Broad Spectrum SPF30

    Multiple defense sun protection system that provides broad spectrum UVA/UVB defense with a universal tint and a silky matte finish.

  • Exclusive 12-hour time-release antioxidant complex guards against photodamage
  • Provides daily multi-defense protection from UVA, UVB and high-energy visible (HEV) light
  • Can be used alone or worn under makeup for a more even, long-lasting application
  • Helps to smooth the skin and diminish the appearance of fine lines